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Diel R, Nienhaus A, Loddenkemper R. Cost effectiveness of interferon-y release assay screening for latent tuberculosis infection treatment in Germany. Chest 2007; 131: 1424-1434.

Oelemann MC, Diel R, Vatin V, Haas W, Rüsch-Gerdes S, Locht C, Niemann S, Supply P. Assessment of an optimized mycobacterial interspersed repetitive- unit-variable-number tandem-repeat typing system combined with spoligotyping for population-based molecular epidemiology studies of tuberculosis. J Clin Microbiol 2007; 45: 691-697.

Nienhaus A, Schablon A, Bâcle CL, Siano B, Diel R. Evaluation of the interferon-gamma release assay in healthcare workers. Int Arch Occup Environ Health 2007; Jun 29 [Epub ahead of print].

Diel R, Loddenkemper R, Meywald-Walter K, Niemann S, Nienhaus A. Predictive value of a whole-blood IFN-{gamma} assay for the development of active TB disease. Am J Resp Crit Care Med 2008; Feb 14 [Epub ahead of print].

Diel R, Loddenkemper R, Meywald-Walter K, Gottschalk R, Nienhaus A. Comparative performance of tuberculin skin test, QuantiFERON-TB-Gold In Tube assay, and T-Spot.TB test in contact investigations for tuberculosis. Chest. 2009;135:1010-8. Epub 2008 Nov 18.

Diel R, Schaberg T, Loddenkemper R, Welte T, Nienhaus A. Enhanced cost-benefit analysis of strategies for LTBI screening and INH chemoprevention in Germany. Respir Med. 2009 Aug 12. [Epub ahead of print]

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Schaberg T, Bauer T, Dalhoff K, Ewig S, Köhler D, Lorenz J, Pletz MW, Rohde G, Rousseau S, Schaaf B, Suttorp N, Welte T. Management of a new influenza A/H1N1 virus pandemic within the hospital: statement of the German Society of Pneumology. Pneumologie. 2009 Aug;63(8):417-25. Epub 2009 Aug 7. German. PubMed PMID: 19670099.

Krüger S, Ewig S, Papassotiriou J, Kunde J, Marre R, von Baum H, Suttor N, Welte T; CAPNETZ Study Group. Inflammatory parameters predict etiologic patterns but do not allow for individual prediction of etiology in patients with CAP: results from the German competence network CAPNETZ. Respir Res. 2009 Jul 12;10:65. PubMed PMID: 19594893; PubMed Central PMCID: PMC2714042.

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Butler CC, Hood K, Verheij T, Little P, Melbye H, Nuttall J, Kelly MJ, Mölstad S, Godycki-Cwirko M, Almirall J, Torres A, Gillespie D, Rautakorpi U, Coenen S, Goossens H. (GRACE Study GROUP). Variation in antibiotic prescribing and its impact on recovery in patients with acute cough in primary care: prospective study in 13 countries. BMJ. 2009; 338

Krüger S, Ewig S, Kunde J, Hanschmann A, Marre R, Suttorp N, Welte T; CAPNETZ Study Group. C-terminal provasopressin (copeptin) in patients with community-acquired pneumonia--influence of antibiotic pre-treatment: results from the German competence network CAPNETZ. J Antimicrob Chemother. 2009;64(1):159-62.

Eker B, Ortmann J, Migliori GB, Sotgiu G, Muetterlein R, Centis R, Hoffmann H, Kirsten D, Schaberg T, Ruesch-Gerdes S, Lange C; German TBNET Group. Multidrug- and extensively drug-resistant tuberculosis, Germany. Emerg Infect Dis. 2008;14(11):1700-6.

Krüger S, Ewig S, Marre R, Papassotiriou J, Richter K, von Baum H, Suttorp N, Welte T; CAPNETZ Study Group. Procalcitonin predicts patients at low risk of death from community-acquired pneumonia across all CRB-65 classes. Eur Respir J. 2008;31(2):349-55.

Kothe H, Bauer T, Marre R, Suttorp N, Welte T, Dalhoff K; the CAPNETZ study group. Outcome of CAP: influence of age, residence status, and antimicrobial treatment. Eur Respir J. 2008;32(1):139-46.

von Baum H, Ewig S, Marre R, Suttorp N, Gonschior S, Welte T, Lück C. Competence Network for Community Acquired Pneumonia Study Group. Community-acquired Legionella pneumonia: new insights from the German competence network for community acquired pneumonia. Clin Infect Dis. 2008;46(9):1356-64.

Schnoor M, Klante T, Beckmann M, Robra BP, Welte T, Raspe H, Schäfer T. CAPNETZ Study Group. Risk factors for community-acquired pneumonia in German adults: the impact of children in the household. Epidemiol Infect. 2007;135(8):1389-97.

Schnoor M, Hedicke J, Dalhoff K, Raspe H, Schäfer T; CAPNETZ study group. Approaches to estimate the population-based incidence of community acquired pneumonia. J Infect. 2007;55(3):233-9.

Krüger S, Papassotiriou J, Marre R, Richter K, Schumann C, von Baum H, Morgenthaler NG, Suttorp N, Welte T; CAPNETZ Study Group. Pro-atrial natriuretic peptide and pro-vasopressin to predict severity and prognosis in community-acquired pneumonia: results from the German competence network CAPNETZ. Intensive Care Med. 2007;33(12):2069-78.

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D. Jullien, S. Stenger, W. Ernst, R. Modlin. CD1 presentation of microbial antigens to T cells. J. Clin. Invest. 99: 2071-2074, 1997

S. Stenger, R. L. Modlin. Cytotoxic T-cell responses to intracellular pathogens. Curr. Opin. Immunol. 10: 471-477, 1998.

S. Stenger, D. Hanson, R. Teitelbaum, P. Dewan, K. R. Niazi, C. J. Froelich, T. Ganz, S. Thoma-Uszynski, A. Melian, C. Bogdan, S.A. Porcelli, B. R. Bloom, A. M. Krensky, R. L. Modlin. An antimicrobial activity of cytolytic T cells mediated by granulysin. Science, 282: 121-125, 1998.

S. Stenger, B. Bloom, A. Krensky, R. Modlin. Granulysin: a lethal weapon of cytolytic T cells. Immunology Today, 20: 390-394, 1999.

S. Thoma-Uszinski*, S. Stenger*, O. Takeuchi, M.-T. Ochoa, P. Sieling, P. Barnes, M. Röllinghoff, P- Bölcskei, M. Wagner, S. Akira, M. Norgard, J. Belisle, P. Godowski, B. Bloom, R. Modlin. Activation of mammalian Toll-like receptors induces a microbicidal activity. Science, 291: 1544-1547, 2001. *equal contribution

M.-T. Ochoa, S. Stenger*, P.A. Sieling*S. Thoma-Uszynski, S. Sabet, S. Cho, A.M. Krensky, M. Röllinghoff, E. Nunes Sarno, A. Burdick, T.H. Rea and R.L. Modlin. A role for the antimicrobial protein granulysin in host defense in leprosy. Nat. Med., 7: 174-179, 2001. *equal contribution

S. Stenger and R. L. Modlin, Control of Mycobacterium tuberculosis through mammalian Toll like receptors. Curr. Opin. Immunol., 14: 452-457, 2002.

M. Engele, E. Stößel, K. Castiglione, N. Schwerdtner, M. Wagner, P. Bölcskei, M. Röllinghoff and S. Stenger. Induction of Tumor Necrosis Factor in human alveolar macrophages as a potential evasion mechanism of virulent Mycobacterium tuberculosis. J. Immunol., 168: 1328-1337, 2002. (IF 6,068)

J. Gansert, V. Kießler, M. Engele, F. Wittcke, S. Porcelli, A. Krensky, M. Röllinghoff, R. Modlin and S. Stenger. NK T cells express granulysin and exhibit antimycobacterial activity. J. Immunol., 170: 3154-3161, 2003.

M. Gilleron*, S. Stenger*, Z. Mazorra, F. Wittke, S. Mariotti, G. Böhmer, L. Mori, G. Puzo, G. DeLibero. Diacylated sulfoglycolipids are novel mycobacterial antigens stimulating CD1-restricted T cells during infection with Mycobacterium tuberculosis. J. Exp. Med., 199: 649. 2004. *equal contribution

M. Büttner, C. Meinken, E. Stößel, R. Bhat, G. Faller, G. Cianciolo, J. Ficker, M. Wagner, M. Röllinghoff, S. Stenger. Inverse correlation of maturity and antibacterial activity in human dendritic cells. J. Immunol., 174: 4203, 2005.

F. Stegelmann, M. Bastian, K. Swoboda, R. Bhat, V. Kießler, A, Krensky, M. Röllinghoff, R. Modlin, S. Stenger. Coordinate expression of CCL5, granulysin and perforin in CD8+ T cells provides a host defense mechanism against M. tuberculosis. J. Immunol., 175: 7474, 2005.

P. Liu*, S. Stenger*, H. Li, L. Wenzel, B. Tan, J. Schauber, K. Wu, C. Meinken, M. Wagner, R. Bals, A. Steinmeyer, U. Zügel, R. Gallo, D. Eisenberg, M. Hewinson, B. Hollis, J. Adams, B. Bloom, R. Modlin. Activation of human TLR2/1 triggers a vitamin D receptor antimicrobial response. Science, 311: 1669, 2006. *equal contribution

B. Tan, C. Meinken, M. Bastian, B. Bloom, T. Ganz, R. Modlin, S. Stenger. Macrophages acquire neutrophil granules for antimicrobial activity against intracellular granules. J. Immunol., 2006, 177: 1864, 2006

Max Bastian, Tobias Braun, Heiko Bruns, Martin Röllinghoff, S. Stenger. Mycobacterial Lipopeptides Elicit CD4+ Cytolytic T Lymphocytes in Mycobacterium tuberculosis Infected Humans. J. Immunol., 180: 3436-3446, 2008.

Heiko Bruns, Christoph Meinken, Philipp Schauenberg, Georg Härter, Peter Kern, Robert L. Modlin, Christian Antoni, S. Stenger. Anti-TNF immunotherapy reduces CD8+ T cell-mediated antimicrobial activity against Mycobacterium tuberculosis. J. Clin. 119(5): 1167-1177, 2009

Mack U, Migliori GB, Sester M, Rieder HL, Ehlers S, Goletti D, Bossink A, Magdorf K, Hölscher C, Kampmann B, Arend SM, Detjen A, Bothamley G, Zellweger JP, Milburn H, Diel R, Ravn P, Cobelens F, Cardona PJ, Kan B, Solovic I, Duarte R, Cirillo DM; C. Lange; TBNET. LTBI: latent tuberculosis infection or lasting mmune responses to M. tuberculosis? A TBNET consensus statement. Eur Respir J. 2009 May;33(5):956-73. PubMed PMID: 19407047.

Ehlers S. Lazy, dynamic or minimally recrudescent? On the elusive nature and location of the mycobacterium responsible for latent tuberculosis. Infection. 2009 Apr;37(2):87-95. Epub 2009 Mar 23. PubMed PMID: 19308316.

Aly S, Mages J, Reiling N, Kalinke U, Decker T, Lang R, Ehlers S. Mycobacteria-induced granuloma necrosis depends on IRF-1. J Cell Mol Med. 2008 Aug 14. [Epub ahead of print] PubMed PMID: 18705699.

Schreiber O, Steinwede K, Ding N, Srivastava M, Maus R, Länger F, Prokein J, Ehlers S, Welte T, Gunn MD, Maus UA. Mice that overexpress CC chemokine ligand 2 in their lungs show increased protective immunity to infection with Mycobacterium bovis bacille Calmette-Guérin. J Infect Dis. 2008 Oct 1;198(7):1044-54. PubMed PMID: 18694332.

Schaefer M, Reiling N, Fessler C, Stephani J, Taniuchi I, Hatam F, Yildirim AO, Fehrenbach H, Walter K, Ruland J, Wagner H, Ehlers S, Sparwasser T. Decreased pathology and prolonged survival of human DC-SIGN transgenic mice during mycobacterial infection. J Immunol. 2008 May 15;180(10):6836-45. PubMed PMID: 18453604.

Hölscher C, Reiling N, Schaible UE, Hölscher A, Bathmann C, Korbel D, Lenz I, Sonntag T, Kröger S, Akira S, Mossmann H, Kirschning CJ, Wagner H, Freudenberg M, Ehlers S. Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9. Eur J Immunol. 2008 Mar;38(3):680-94. PubMed PMID: 18266299.

Reiling N, Ehlers S, Hölscher C. MyDths and un-TOLLed truths: sensor, instructive and effector immunity to tuberculosis. Immunol Lett. 2008 Feb 15;116(1):15-23. Epub 2007 Dec 26. Review. PubMed PMID: 18191460.

Lange C, Hellmich B, Ernst M, Ehlers S. Rapid immunodiagnosis of tuberculosis in a woman receiving anti-TNF therapy. Nat Clin Pract Rheumatol. 2007 Sep;3(9):528-34. PubMed PMID: 17762852.

Aly S, Laskay T, Mages J, Malzan A, Lang R, Ehlers S. Interferon-gamma-dependent mechanisms of mycobacteria-induced pulmonary immunopathology: the role of angiostasis and CXCR3-targeted chemokines for granuloma necrosis. J Pathol. 2007 Jul;212(3):295-305. PubMed PMID: 17534845.

Srivastava M, Meinders A, Steinwede K, Maus R, Lucke N, Bühling F, Ehlers S, Welte T, Maus UA. Mediator responses of alveolar macrophages and kinetics of mononuclear phagocyte subset recruitment during acute primary and secondary mycobacterial infections in the lungs of mice. Cell Microbiol. 2007 Mar;9(3):738-52. Epub 2006 Oct 18. PubMed PMID: 17054437.

Aly S, Wagner K, Keller C, Malm S, Malzan A, Brandau S, Bange FC, Ehlers S. Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice. J Pathol. 2006 Nov;210(3):298-305. PubMed PMID: 17001607.

Keller C, Hoffmann R, Lang R, Brandau S, Hermann C, Ehlers S. Genetically determined susceptibility to tuberculosis in mice causally involves accelerated and enhanced recruitment of granulocytes. Infect Immun. 2006 Jul;74(7):4295-309. PubMed PMID: 16790804; PubMed Central PMCID: PMC1489748.

Blumenthal A, Lauber J, Hoffmann R, Ernst M, Keller C, Buer J, Ehlers S, Reiling N. Common and unique gene expression signatures of human macrophages in response to four strains of Mycobacterium avium that differ in their growth and persistence characteristics. Infect Immun. 2005 Jun;73(6):3330-41. PubMed PMID: 15908359; PubMed Central PMCID: PMC1111816.

Hölscher C, Hölscher A, Rückerl D, Yoshimoto T, Yoshida H, Mak T, Saris C, Ehlers S. The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis. J Immunol. 2005 Mar 15;174(6):3534-44. PubMed PMID: 15749890.

Keller C, Lauber J, Blumenthal A, Buer J, Ehlers S. Resistance and susceptibility to tuberculosis analysed at the transcriptome level: lessons from mouse macrophages. Tuberculosis (Edinb). 2004;84(3-4):144-58. PubMed PMID: 15207484.

Krawczak M, Nikolaus S, von Eberstein H, Croucher PJ, El Mokhtari NE, Schreiber S. PopGen: Population-Based Recruitment of Patients and Controls for the Analysis of Complex Genotype-Phenotype Relationships. 2006 Community Genet. 9(1): 55-61.